Schumacher Lab Publications

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The novel role of lymphatic vessels in the pathogenesis of ocular diseases.

Clahsen T, Hadrian K, Notara M, Schlereth SL, Howaldt A, Prokosch V, Volatier T, Hos D, Schroedl F, Kaser-Eichberger A, Heindl LM, Steven P, Bosch JJ, Steinkasserer A, Rokohl AC, Liu H, Mestanoglu M, Kashkar H, Schumacher B, Kiefer F, Schulte-Merker S, Matthaei M, Hou Y, Fassbender S, Jantsch J, Zhang W, Enders P, Bachmann B, Bock F, Cursiefen C.
Prog Retin Eye Res. 2023 Feb 7:101157.
https://doi.org/10.1016/j.preteyeres.2022.101157

Perinatal Obesity Sensitizes for Premature Kidney Aging Signaling
Selle J, Bohl K, Höpker K, Wilke R, Dinger K, Kasper P, Abend B, Schermer B, Müller R, Kurschat C, Nüsken K, Nüsken E, Meyer D, Savai Pullamsetti S, Schumacher B, Dötsch J, Alejandre Alcazar M,
Int. J. Mol. Sci. 2023, 24(3), 2508;
https://doi.org/10.3390/ijms24032508

Inheritance of paternal DNA damage by histone-mediated repair restriction.

Wang, S., Meyer, D.H. & Schumacher, B.
Nature
2023 Jan;613(7943):365-374.
https://doi.org/10.1038/s41586-022-05544-w

Perinatal Obesity Induces Hepatic Growth Restriction with Increased DNA Damage Response, Senescence, and Dysregulated Igf-1-Akt-Foxo1 Signaling in Male Offspring of Obese Mice.

Kasper P, Selle J, Vohlen C, Wilke R, Kuiper-Makris C, Klymenko O, Bae-Gartz I, Schömig C, Quaas A, Schumacher B, Demir M, Bürger M, Lang S, Martin A, Steffen HM, Goeser T, Dötsch J, Alcazar MAA.

The p53 network: cellular and systemic DNA damage responses in cancer and aging.

Vaddavalli PL, Schumacher B.
The p53 network: cellular and systemic DNA damage responses in cancer and aging.
Trends Genet. 2022 Jun;38(6):598-612. doi: 10.1016/j.tig.2022.02.010. Epub 2022 Mar 25.
https://pubmed.ncbi.nlm.nih.gov/35346511/

UV Protection in the Cornea: Failure and Rescue

Volatier T, Schumacher B, Cursiefen C, Notara M.
UV Protection in the Cornea: Failure and Rescue.
Biology (Basel). 2022 Feb 10;11(2):278. doi: 10.3390/biology11020278.
https://pubmed.ncbi.nlm.nih.gov/35205145/

Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity.

Umansky C, Morellato AE, Rieckher M, Scheidegger MA, Martinefski MR, Fernández GA, Pak O, Kolesnikova K, Reingruber H, Bollini M, Crossan GP, Sommer N, Monge ME, Schumacher B, Pontel LB.
Endogenous formaldehyde scavenges cellular glutathione resulting in redox disruption and cytotoxicity.
Nat Commun. 2022 Feb 8;13(1):745. doi: 10.1038/s41467-022-28242-7.
https://pubmed.ncbi.nlm.nih.gov/35136057/

Somatic PMK-1/p38 signaling links environmental stress to germ cell apoptosis and heritable euploidy.

Soltanmohammadi N, Wang S, Schumacher B.
Somatic PMK-1/p38 signaling links environmental stress to germ cell apoptosis and heritable euploidy.
Nat Commun. 2022 Feb 4;13(1):701. doi: 10.1038/s41467-022-28225-8.
https://www.nature.com/articles/s41467-022-28225-8

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