Schumacher Lab Publications

Ermolaeva MA, Schumacher B.
Systemic DNA damage responses: organismal adaptations to genome instability.
Trends Genet. 2014 Mar;30(3):95-102. doi: 10.1016/j.tig.2013.12.001. Epub 2014 Jan 15.

Wolters S, Ermolaeva MA, Bickel JS, Fingerhut JM, Khanikar J, Chan RC, Schumacher B.
Loss of Caenorhabditis elegans BRCA1 Promotes Genome Stability During Replication in smc-5 Mutants.
Genetics. 2014 Apr;196(4):985-99. doi: 10.1534/genetics.113.158295. Epub 2014 Jan 14.

Ermolaeva M, Schumacher B.
The innate immune system as mediator of systemic DNA damage responses.
Communicative & Integrative Biology 2013; 6:e26926; doi:10.4161/cib.26926

Ermolaeva MA, Segref A, Dakhovnik A, Ou HL, Schneider JI, Utermöhlen O, Hoppe T, Schumacher B.
DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance.
Nature. 2013 Sep 19;501(7467):416-20. doi: 10.1038/nature12452.

Schermer B, Bartels V, Frommolt P, Habermann B, Braun F, Schultze JL, Roodbergen M, Hoeijmakers JH, Schumacher B, Nürnberg P, Dollé ME, Benzing T, Müller RU,
Kurschat CE.
Transcriptional profiling reveals progeroid Ercc1-/Δ mice as a model system for glomerular ageing.
BMC Genomics. 2013 Aug 16;14:559. doi: 10.1186/1471-2164-14-559.

Wolters S, Schumacher B
Genome maintenance and transcription integrity in aging and disease.
Front Genet. 2013;4:19. doi: 10.3389/fgene.2013.00019. Epub 2013 Feb 25

Schumacher B
DNA-Reparatur und Alterung
Medgen. 2012; 24: 289-296

Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos ML, Thomas RK, Lowery D, Roels F, Fischer M, Liebau MC, Resch U, Kisner T, Röther F, Bartram MP, Ulrich Müller R, Fabretti F, Kurschat P, Schumacher B, Gaestel M, Medema RH, Yaffe MB, Schermer B, Christian Reinhardt H, Benzing T
AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repressp53-driven apoptosis.
EMBO J. 2012 Aug 21.

Reinhardt HC, Schumacher B
The p53 network: Cellular and systemic DNA damage responses in aging and cancer.
Trends Genet. 2012 Mar;28(3):128-36.